Structural domains in RNAi.
نویسندگان
چکیده
Structural and biochemical studies have begun to elucidate the pathway of RNA silencing that leads to the formation of the RISC complex. The outstanding feature of this pathway is the precise recognition and processing of double-stranded RNA. We present a review of recent structures that illustrate the molecular mechanisms contributing to these two related functions, highlighting models of Drosha, Dicer, and RISC function.
منابع مشابه
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ورودعنوان ژورنال:
- FEBS letters
دوره 579 26 شماره
صفحات -
تاریخ انتشار 2005